Immune deficiency due to adenosine deaminase and purine nucleoside phosphorylase deficiency: a simple diagnostic test.

نویسندگان

  • J L Maddocks
  • S A Al-Safi
  • G Wilson
چکیده

A simple method is described for diagnosing adenosine deaminase and purine nucleoside phosphorylase deficiency using urine. Cellulose thin layer chromatography of 1 microliter of urine from affected children was performed and deoxyadenosine and deoxyguanosine were easily detected by phosphorescence at the temperature of liquid nitrogen. This test is not expensive and can be done in any laboratory. It should be suitable for diagnostic screening in patients with immune deficiency.

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عنوان ژورنال:
  • Journal of clinical pathology

دوره 37 11  شماره 

صفحات  -

تاریخ انتشار 1984